COVID-19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin.

Theoharides, Theoharis C

Theoharides, Theoharis C.

Theoharides TC; Laboratory of Molecular Immunopharmacology and Drug Discovery, Department of Immunology, Tufts University School of Medicine, Boston, MA.

Biofactors ; 46(3): 306-308, 2020 05.

Article in English | MEDLINE | ID: covidwho-125444

Subject(s)

Antiviral Agents/therapeutic use; Coronavirus Infections/drug therapy; Cytokine Release Syndrome/prevention & control; Luteolin/therapeutic use; Pneumonia, Viral/drug therapy; Respiratory System Agents/therapeutic use; Spike Glycoprotein, Coronavirus/genetics; Angiotensin-Converting Enzyme 2; Betacoronavirus/drug effects; Betacoronavirus/pathogenicity; COVID-19; Coronavirus Infections/immunology; Coronavirus Infections/pathology; Coronavirus Infections/virology; Cytokine Release Syndrome/immunology; Cytokine Release Syndrome/pathology; Cytokine Release Syndrome/virology; Humans; Lung/drug effects; Lung/immunology; Lung/virology; Mast Cells/drug effects; Mast Cells/immunology; Mast Cells/virology; Pandemics; Peptidyl-Dipeptidase A/genetics; Peptidyl-Dipeptidase A/immunology; Pneumonia, Viral/immunology; Pneumonia, Viral/pathology; Pneumonia, Viral/virology; Quercetin/therapeutic use; Renin-Angiotensin System/drug effects; Renin-Angiotensin System/genetics; Renin-Angiotensin System/immunology; Research Design; SARS-CoV-2; Severity of Illness Index; Spike Glycoprotein, Coronavirus/antagonists & inhibitors; Spike Glycoprotein, Coronavirus/immunology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Pneumonia, Viral / Coronavirus Infections / Respiratory System Agents / Luteolin / Spike Glycoprotein, Coronavirus / Cytokine Release Syndrome Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Biofactors Journal subject: Biochemistry Year: 2020 Document Type: Article Affiliation country: Biof.1633

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