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Acute abdomen in a 54-year-old COVID-19 patient: a case teport.
Holleb, Peter; Patel, Priya; Saxena, Pranay; Beniwal, Jagbir; Zuberi, Jamshed.
  • Holleb P; St. George's University School of Medicine, True Blue, Grenada, West Indies.
  • Patel P; St. George's University School of Medicine, True Blue, Grenada, West Indies.
  • Saxena P; Department of Surgery, CarePoint Health, Bayonne, NJ, USA.
  • Beniwal J; Department of Surgery, St. Joseph's University Medical Center, Paterson, NJ, USA.
  • Zuberi J; Department of Surgery, St. Joseph's University Medical Center, Paterson, NJ, USA.
J Surg Case Rep ; 2021(5): rjab198, 2021 May.
Article in English | MEDLINE | ID: covidwho-1254792
ABSTRACT
Although primarily a respiratory virus, coronavirus-19 acts on the gastrointestinal tract to cause symptoms such as anorexia, nausea, vomiting and diarrhea. One possible mechanism involves the ACE2 receptor, which serves as the primary receptor for virus entry into the gastrointestinal epithelium. We describe the case of a 54-year-old-male with recent coronavirus disease 2019 (COVID-19) infection, who later presented with nausea, vomiting, diarrhea and progressively worsening diffuse abdominal pain for 1 week. He was diagnosed to have a small bowel obstruction; however, continued to have progressively worsening pain and failed conservative management. No cause for the obstruction was found in the operating room. Gastrointestinal involvement occurs in at least two-thirds of patients with coronavirus infection. Viral entry into the small bowel, triggering an inflammatory response, and virus-induced microthrombosis of the microcirculation have been postulated as a possible mechanism for paralytic ileus/small bowel obstruction.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: J Surg Case Rep Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: J Surg Case Rep Year: 2021 Document Type: Article