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Clinical features, management, and outcome of hemodialysis patients with SARS-CoV-2.
Sahin, Burcin; Kose, Sennur; Eren, Gulhan; Yoruk, Gulsen.
  • Sahin B; Department of Infectious Diseases, SBU Istanbul Training and Research Hospital, Istanbul, Turkey.
  • Kose S; Department of Nephrology, SBU Istanbul Training and Research Hospital, Istanbul, Turkey.
  • Eren G; Department of Infectious Diseases, SBU Istanbul Training and Research Hospital, Istanbul, Turkey.
  • Yoruk G; Department of Infectious Diseases, SBU Istanbul Training and Research Hospital, Istanbul, Turkey.
Ther Apher Dial ; 26(1): 171-177, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1255062
ABSTRACT
The aim of the study was to evaluate the clinical features of the patients on HD with COVID-19 and determine the prognostic factors. In this single-center prospective study, a total of 58 chronic renal failure patients on HD and diagnosed COVID-19 infection were enrolled in the study. The patients were divided into two groups according to their need for intensive care unit referral. Demographic features of the patients, clinical manifestations, laboratory data, treatments, and clinical outcome were evaluated. The mean age of 58 HD patients was 63.2 ± 13.8 (30-93) years and female-male ratio was 0.34. SARS-CoV2-PCR positivity rate was 32.8%. 85.2% of patients (n = 46) had bilateral lesions and 14.8% (n = 8) had unilateral one lesion in chest CT. The most common symptoms were fatigue (in 44 patients, 80%) and dyspnea (in 31 patients, 56.4%). The most common comorbidity was HT (in 37 patients, 67.3%). The patients who need intensive care and died were older (p = 0.015). We observed lower platelet and eosinophil counts, potassium levels, higher AST, troponin and CRP levels in the group of patients who need intensive care and died than the group who survived (p = 0.043, 0.005, 0.033, 0.007, 0.001, <0.001, respectively). 15.5% of the patients (n = 9) were transferred to intensive care unit. Among them, two were discharged with cure and seven patients died. Mortality rate was 12.1%. Older age, lower platelet and eosinophil counts and higher AST, troponin and CRP levels were prognostic risk factors in our HD patients who needed intensive care.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Renal Dialysis / COVID-19 / Kidney Failure, Chronic Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Ther Apher Dial Journal subject: Hematology Year: 2022 Document Type: Article Affiliation country: 1744-9987.13696

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Renal Dialysis / COVID-19 / Kidney Failure, Chronic Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Ther Apher Dial Journal subject: Hematology Year: 2022 Document Type: Article Affiliation country: 1744-9987.13696