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Infection related catheter complications in patients undergoing prone positioning for acute respiratory distress syndrome: an exposed/unexposed study.
Louis, Guillaume; Belveyre, Thibaut; Jacquot, Audrey; Hochard, Hélène; Aissa, Nejla; Kimmoun, Antoine; Goetz, Christophe; Levy, Bruno; Novy, Emmanuel.
  • Louis G; Intensive Care Unit, Metz-Thionville Regional Hospital, Mercy Hospital, 1 allée de Château, 57085, Metz, France. g.louis@chr-metz-thionville.fr.
  • Belveyre T; Intensive Care Unit, Metz-Thionville Regional Hospital, Mercy Hospital, 1 allée de Château, 57085, Metz, France.
  • Jacquot A; Medical intensive Care Unit, University Hospital of Nancy, Brabois, France.
  • Hochard H; Department of Bacteriology, Metz-Thionville Regional Hospital, Mercy Hospital, Metz, France.
  • Aissa N; Department of Bacteriology, University Hospital of Nancy, Nancy, France.
  • Kimmoun A; Medical intensive Care Unit, University Hospital of Nancy, Brabois, France.
  • Goetz C; Clinical Research Support Unit, Metz-Thionville Regional Hospital, Metz, France.
  • Levy B; Medical intensive Care Unit, University Hospital of Nancy, Brabois, France.
  • Novy E; Intensive Care Unit, Metz-Thionville Regional Hospital, Mercy Hospital, 1 allée de Château, 57085, Metz, France.
BMC Infect Dis ; 21(1): 534, 2021 Jun 07.
Article in English | MEDLINE | ID: covidwho-1257922
ABSTRACT

BACKGROUND:

Prone positioning (PP) is a standard of care for patients with moderate-severe acute respiratory distress syndrome (ARDS). While adverse events associated with PP are well-documented in the literature, research examining the effect of PP on the risk of infectious complications of intravascular catheters is lacking.

METHOD:

All consecutive ARDS patients treated with PP were recruited retrospectively over a two-year period and formed the exposed group. Intensive care unit (ICU) patients during the same period without ARDS for whom PP was not conducted but who had an equivalent disease severity were matched 11 to the exposed group based on age, sex, centre, length of ICU stay and SAPS II (unexposed group). Infection-related catheter complications were defined by a composite criterion, including catheter tip colonization or intravascular catheter-related infection.

RESULTS:

A total of 101 exposed patients were included in the study. Most had direct ARDS (pneumonia). The median [Q1-Q3] PP session number was 2 [1-4]. These patients were matched with 101 unexposed patients. The mortality rates of the exposed and unexposed groups were 31 and 30%, respectively. The incidence of the composite criterion was 14.2/1000 in the exposed group compared with 8.2/1000 days in the control group (p = 0.09). Multivariate analysis identified PP as a factor related to catheter colonization or infection (p = 0.04).

CONCLUSION:

Our data suggest that PP is associated with a higher risk of CVC infectious complications.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Catheter-Related Infections / Patient Positioning Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: BMC Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: S12879-021-06197-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Catheter-Related Infections / Patient Positioning Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: BMC Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: S12879-021-06197-2