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Healthcare workers acquired COVID-19 disease from patients? An investigation by phylogenomics.
Wong, R C W; Lee, M K P; Siu, G K H; Lee, L K; Leung, J S L; Leung, E C M; Ho, Y I I; Lai, R W M.
  • Wong RCW; Department of Microbiology, Prince of Wales Hospital, Hong Kong SAR, China. Electronic address: wcw372@ha.org.hk.
  • Lee MKP; Department of Microbiology, Prince of Wales Hospital, Hong Kong SAR, China.
  • Siu GKH; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China.
  • Lee LK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China.
  • Leung JSL; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China.
  • Leung ECM; Department of Microbiology, Prince of Wales Hospital, Hong Kong SAR, China.
  • Ho YII; Department of Microbiology, Prince of Wales Hospital, Hong Kong SAR, China.
  • Lai RWM; Department of Microbiology, Prince of Wales Hospital, Hong Kong SAR, China.
J Hosp Infect ; 115: 59-63, 2021 Sep.
Article in English | MEDLINE | ID: covidwho-1258421
ABSTRACT
The increasing number of coronavirus disease 2019 (COVID-19) cases in the community has posed a significant epidemic pressure on healthcare settings. When healthcare workers (HCWs) acquire COVID-19, contact tracing and epidemiological investigation might not be adequate for determining the source of transmission. Here, we report a phylogenetic investigation involving two infected HCWs and nine patients to determine whether patient-to-HCW transmission had occurred in a hospital without a previous COVID-19 outbreak. This is the first study to apply phylogenomics to investigate suspected nosocomial transmission in a region with low prevalence of COVID-19. Our results do not support the occurrence of direct patient-to-HCW transmission.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Randomized controlled trials Limits: Humans Language: English Journal: J Hosp Infect Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Randomized controlled trials Limits: Humans Language: English Journal: J Hosp Infect Year: 2021 Document Type: Article