Your browser doesn't support javascript.
Drug and alcohol positivity of traumatically injured patients related to COVID-19 stay-at-home orders.
Young, Kirsten N; Yeates, Eric O; Grigorian, Areg; Schellenberg, Morgan; Owattanapanich, Natthida; Barmparas, Galinos; Margulies, Daniel; Juillard, Catherine; Garber, Kent; Cryer, Henry; Tillou, Areti; Burruss, Sigrid; Penaloza-Villalobos, Liz; Lin, Ann; Figueras, Ryan Arthur; Brenner, Megan; Firek, Christopher; Costantini, Todd; Santorelli, Jarrett; Curry, Terry; Wintz, Diane; Biffl, Walter L; Schaffer, Kathryn B; Duncan, Thomas K; Barbaro, Casey; Diaz, Graal; Johnson, Arianne; Chinn, Justine; Naaseh, Ariana; Leung, Amanda; Grabar, Christina; Nahmias, Jeffry.
  • Young KN; Department of Surgery, University of California, Irvine, CA, USA.
  • Yeates EO; Department of Surgery, University of California, Irvine, CA, USA.
  • Grigorian A; Department of Surgery, University of California, Irvine, CA, USA.
  • Schellenberg M; Department of Surgery, University of Southern California, Los Angeles, CA, USA.
  • Owattanapanich N; Department of Surgery, University of Southern California, Los Angeles, CA, USA.
  • Barmparas G; Department of Surgery, University of Southern California, Los Angeles, CA, USA.
  • Margulies D; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Juillard C; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Garber K; Department of Surgery, University of California, Los Angeles, CA, USA.
  • Cryer H; Department of Surgery, University of California, Los Angeles, CA, USA.
  • Tillou A; Department of Surgery, University of California, Los Angeles, CA, USA.
  • Burruss S; Department of Surgery, University of California, Los Angeles, CA, USA.
  • Penaloza-Villalobos L; Department of Surgery, Loma Linda University, Loma Linda, CA, USA.
  • Lin A; Department of Surgery, Loma Linda University, Loma Linda, CA, USA.
  • Figueras RA; Department of Surgery, Loma Linda University, Loma Linda, CA, USA.
  • Brenner M; Department of Surgery, Loma Linda University, Loma Linda, CA, USA.
  • Firek C; Riverside/Riverside University Health System Department of Surgery, University of California, Moreno Valley, CA, USA.
  • Costantini T; Riverside University Health System, Comparative Effectiveness and Clinical Outcomes Research Center (CECORC), Moreno Valley, CA, USA.
  • Santorelli J; Department of Surgery, University of California, San Diego, CA, USA.
  • Curry T; Department of Surgery, University of California, San Diego, CA, USA.
  • Wintz D; Department of Surgery, University of California, San Diego, CA, USA.
  • Biffl WL; Department of Surgery, Sharp Memorial Hospital, San Diego, CA, USA.
  • Schaffer KB; Trauma Department, Scripps Memorial Hospital La Jolla, La Jolla, CA, USA.
  • Duncan TK; Trauma Department, Scripps Memorial Hospital La Jolla, La Jolla, CA, USA.
  • Barbaro C; Department of Surgery, Ventura County Medical Center, Ventura, CA, USA.
  • Diaz G; Department of Surgery, Ventura County Medical Center, Ventura, CA, USA.
  • Johnson A; Department of Surgery, Ventura County Medical Center, Ventura, CA, USA.
  • Chinn J; Department of Trauma, Santa Barbara Cottage Hospital, Cottage Health Research Institute, Santa Barbara, CA, USA.
  • Naaseh A; Department of Surgery, University of California, Irvine, CA, USA.
  • Leung A; Department of Surgery, University of California, Irvine, CA, USA.
  • Grabar C; Department of Surgery, University of California, Irvine, CA, USA.
  • Nahmias J; Department of Surgery, University of California, Irvine, CA, USA.
Am J Drug Alcohol Abuse ; 47(5): 605-611, 2021 09 03.
Article in English | MEDLINE | ID: covidwho-1258627
ABSTRACT

Background:

COVID-19 related stay-at-home (SAH) orders created many economic and social stressors, possibly increasing the risk of drug/alcohol abuse in the community and trauma population.

Objectives:

Describe changes in alcohol/drug use in traumatically injured patients after SAH orders in California and evaluate demographic or injury pattern changes in alcohol or drug-positive patients.

Methods:

A retrospective analysis of 11 trauma centers in Southern California (1/1/2020-6/30/2020) was performed. Blood alcohol concentration, urine toxicology results, demographics, and injury characteristics were collected. Patients were grouped based on injury date - before SAH (PRE-SAH), immediately after SAH (POST-SAH), and a historical comparison (3/19/2019-6/30/2019) (CONTROL) - and compared in separate analyses. Groups were compared using chi-square tests for categorical variables and Mann-Whitney U tests for continuous variables.

Results:

20,448 trauma patients (13,634 male, 6,814 female) were identified across three time-periods. The POST-SAH group had higher rates of any drug (26.2% vs. 21.6% and 24.7%, OR = 1.26 and 1.08, p < .001 and p = .035), amphetamine (10.4% vs. 7.5% and 9.3%, OR = 1.43 and 1.14, p < .001 and p = .023), tetrahydrocannabinol (THC) (13.8% vs. 11.0% and 11.4%, OR = 1.30 and 1.25, p < .001 and p < .001), and 3,4-methylenedioxy methamphetamine (MDMA) (0.8% vs. 0.4% and 0.2%, OR = 2.02 and 4.97, p = .003 and p < .001) positivity compared to PRE-SAH and CONTROL groups. Alcohol concentration and positivity were similar between groups (p > .05).

Conclusion:

This Southern California multicenter study demonstrated increased amphetamine, MDMA, and THC positivity in trauma patients after SAH, but no difference in alcohol positivity or blood concentration. Drug prevention strategies should continue to be adapted within and outside of hospitals during a pandemic.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Substance Abuse Detection / Substance-Related Disorders / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: North America Language: English Journal: Am J Drug Alcohol Abuse Year: 2021 Document Type: Article Affiliation country: 00952990.2021.1904967

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Substance Abuse Detection / Substance-Related Disorders / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: North America Language: English Journal: Am J Drug Alcohol Abuse Year: 2021 Document Type: Article Affiliation country: 00952990.2021.1904967