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Serosurvey in BNT162b2 vaccine-elicited neutralizing antibodies against authentic B.1, B.1.1.7, B.1.351, B.1.525 and P.1 SARS-CoV-2 variants.
Zani, Alberto; Caccuri, Francesca; Messali, Serena; Bonfanti, Carlo; Caruso, Arnaldo.
  • Zani A; Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Caccuri F; Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Messali S; Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Bonfanti C; Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Caruso A; Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Emerg Microbes Infect ; 10(1): 1241-1243, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1258725
ABSTRACT
In this study, we show that BNT162b2 vaccine-elicited antibodies efficiently neutralize SARS-CoV-2 authentic viruses belonging to B.1, B.1.1.7, B.1.351, B.1.525 and P.1 lineages. Interestingly, the neutralization of B.1.1.7 and B.1.525 lineages was significantly higher, whereas the neutralization of B.1.351 and P.1 lineages was robust but significantly lower as compared to B.1 lineage. Following our findings, we consider that the BNT162b2 vaccine offers protection against the current prevailing variants of SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antibodies, Neutralizing / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Antibodies, Viral Topics: Vaccines / Variants Limits: Humans Language: English Journal: Emerg Microbes Infect Year: 2021 Document Type: Article Affiliation country: 22221751.2021.1940305

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antibodies, Neutralizing / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Antibodies, Viral Topics: Vaccines / Variants Limits: Humans Language: English Journal: Emerg Microbes Infect Year: 2021 Document Type: Article Affiliation country: 22221751.2021.1940305