Rationale of Therapeutic Plasma Exchange as Rescue Immunomodulatory Treatment for MIS-C With Multiorgan Failure.
Pediatr Infect Dis J
; 40(7): e259-e262, 2021 07 01.
Article
in English
| MEDLINE | ID: covidwho-1258812
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection is an infrequent and poorly understood illness. It can present as severe multiorgan failure in children, potentially lethal. Immunomodulation is the empiric treatment because a dysregulated immune response is the primary pathophysiologic mechanism. We present an infant with severe MIS-C, refractory to usual treatment, successfully treated with plasmapheresis.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Plasma Exchange
/
Systemic Inflammatory Response Syndrome
/
Immunomodulation
/
COVID-19
/
Multiple Organ Failure
Type of study:
Case report
/
Prognostic study
Limits:
Child, preschool
/
Female
/
Humans
Language:
English
Journal:
Pediatr Infect Dis J
Journal subject:
Communicable Diseases
/
Pediatrics
Year:
2021
Document Type:
Article
Affiliation country:
Inf.0000000000003169
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