Insights into the potential role of alpha1-antitrypsin in COVID-19 patients: Mechanisms, current update, and future perspectives.
Clin Respir J
; 15(9): 1019-1024, 2021 Sep.
Article
in English
| MEDLINE | ID: covidwho-1258918
ABSTRACT
In this work, we provide an up-to-date summary of the available molecular- and cell-related mechanisms by which alpha1-antitrypsin (AAT) protein could be of benefit in treating COVID-19 patients. As well, we demonstrate the current status in terms of the ongoing clinical trials using AAT in COVID-19 patients. Finally, we touch on the potential role gene therapy and stem cell-based gene therapy could have in such emerging and serious condition caused by the SARS-CoV-2 virus.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Alpha 1-Antitrypsin Deficiency
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Clin Respir J
Year:
2021
Document Type:
Article
Affiliation country:
Crj.13406
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