Your browser doesn't support javascript.
Immune system and COVID-19 by sex differences and age.
Ciarambino, Tiziana; Para, Ombretta; Giordano, Mauro.
  • Ciarambino T; Department of Internal Medicine, Marcianise Hospital, ASL Caserta, Italy.
  • Para O; Department of Internal Medicine, Careggi Hospital, University of Florence, Florence, Italy.
  • Giordano M; Department of Internal Medicine, University of Campania, L. Vanvitelli, Naples, Italy.
Womens Health (Lond) ; 17: 17455065211022262, 2021.
Article in English | MEDLINE | ID: covidwho-1259152
ABSTRACT
In COVID-19 disease, are reported gender differences in relation to severity and death. The aim of this review is to highlight gender differences in the immune response to COVID-19. The included studies were identified using PubMed, until 30 October 2020. The search included the following keywords SARS-CoV-2, COVID-19, gender, age, sex, and immune system. Literature described that females compared to males have greater inflammatory, antiviral, and humoral immune responses. In female, estrogen is a potential ally to alleviate SARS-COV-2 disease. In male, testosterone reduces vaccination response and depresses the cytokine response. In the older patients, and in particular, in female older patients, it has been reported a progressive functional decline in the immune systems. Differences by gender were reported in infection diseases, including SARS-CoV-2. These data should be confirmed by the other epidemiological studies.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Aging / Sex Factors / COVID-19 / Immune System / Immunity Type of study: Observational study / Prognostic study / Reviews Topics: Vaccines Limits: Female / Humans / Male Language: English Journal: Womens Health (Lond) Journal subject: Women's Health Year: 2021 Document Type: Article Affiliation country: 17455065211022262

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Aging / Sex Factors / COVID-19 / Immune System / Immunity Type of study: Observational study / Prognostic study / Reviews Topics: Vaccines Limits: Female / Humans / Male Language: English Journal: Womens Health (Lond) Journal subject: Women's Health Year: 2021 Document Type: Article Affiliation country: 17455065211022262