Two COVID-19-related video-accompanied cases of severe ataxia-myoclonus syndrome.
Neurol Neurochir Pol
; 55(3): 310-313, 2021.
Article
in English
| MEDLINE | ID: covidwho-1259716
ABSTRACT
AIM OF THE STUDY The pandemic state of COVID-19 has resulted in new neurological post-infection syndromes. Recently, several papers have reported ataxia-myoclonus syndrome following SARS-CoV-2 infection. The aim of this study was to present our two cases and compare them to previously reported cases. MATERIALS AND METHODS:
We present two video-accompanied new cases with ataxia-myoclonus syndrome following SARS-CoV-2 infection and discuss the studies published so far.RESULTS:
Ataxia-myoclonus syndrome, isolated myoclonus, opsoclonus-myoclonus syndrome as post-COVID-19 syndrome following infection have been described in 16 patients (including our two cases). Patients have been treated with intravenous immunoglobulins and/or steroids except for 4 patients, which resulted in a significant improvement within 1-8 weeks. CONCLUSIONS AND CLINICAL IMPLICATIONS The increasing number of patients with a similar symptomatology shows a significant relationship between COVID-19 infection and ataxia-myoclonus syndrome. The subacute onset of neurological symptoms after a resolved COVID-19 infection and prominent response to immunotherapy may suggest that the neurological manifestations are immune-mediated. Although recovery is highly possible, it may take several weeks/months, and clinicians should be aware of this diagnosis and the beneficial effects of immunological treatment administered as soon as possible.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Opsoclonus-Myoclonus Syndrome
/
COVID-19
Type of study:
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Neurol Neurochir Pol
Year:
2021
Document Type:
Article
Affiliation country:
PJNNS.a2021.0036
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