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What gastroenterologists should know about SARS-CoV 2 vaccine: World Endoscopy Organization perspective.
Spadaccini, Marco; Canziani, Lorenzo; Aghemo, Alessio; Lleo, Ana; Maselli, Roberta; Anderloni, Andrea; Carrara, Silvia; Fugazza, Alessandro; Pellegatta, Gaia; Galtieri, Piera Alessia; Hassan, Cesare; Greenwald, David; Pochapin, Mark; Wallace, Michael; Sharma, Prateek; Roesch, Thomas; Bhandari, Pradeep; Emura, Fabian; Raju, Gottumukkala S; Repici, Alessandro.
  • Spadaccini M; Department of Biomedical Sciences, Humanitas University, Rozzano, Italy.
  • Canziani L; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Aghemo A; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Lleo A; Department of Internal Medicine, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Maselli R; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Anderloni A; Department of Gastroenterology, Division of Internal Medicine and Hepatology, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Carrara S; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Fugazza A; Department of Gastroenterology, Division of Internal Medicine and Hepatology, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Pellegatta G; Department of Biomedical Sciences, Humanitas University, Rozzano, Italy.
  • Galtieri PA; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Hassan C; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Greenwald D; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Pochapin M; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Wallace M; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Sharma P; Department of Gastroenterology, Endoscopy Unit, Humanitas Clinical and Research Center IRCCS, Rozzano, Italy.
  • Roesch T; Digestive Endoscopy Unit, Nuovo Regina Margherita, Rome, Italy.
  • Bhandari P; Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, New York, USA.
  • Emura F; Division of Gastroenterology and Hepatology, NYU Langone Health, New York, New York, USA.
  • Raju GS; Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA.
  • Repici A; Digestive Endoscopy Unit, Kansas City VA Medical Center, Kansas City, Missouri, USA.
United European Gastroenterol J ; 9(7): 787-796, 2021 09.
Article in English | MEDLINE | ID: covidwho-1260575
ABSTRACT

BACKGROUND:

The novel Coronavirus (SARS-CoV-2) has caused almost 2 million deaths worldwide. Both Food and Drug Administration and European Medicines Agency have recently approved the first COVID-19 vaccines, and a few more are going to be approved soon.

METHODS:

Several different approaches have been used to stimulate the immune system in mounting a humoral response. As more traditional approaches are under investigation (inactivated virus vaccines, protein subunit vaccines, recombinant virus vaccines), more recent and innovative strategies have been tried (non-replicating viral vector vaccines, RNA based vaccines, DNA based vaccines).

RESULTS:

Since vaccinations campaigns started in December 2020 in both the US and Europe, gastroenterologists will be one of the main sources of information regarding SARS-CoV 2 vaccination for patients in their practice, including vulnerable patients such as those with Inflammatory Bowel Disease (IBD), patients with chronic liver disease, and GI cancer patients.

CONCLUSIONS:

Thus, we must ourselves be well educated and updated in order to provide unambiguous counseling to these categories of vulnerable patients. In this commentary, we aim to provide a comprehensive review of both approved COVID-19 vaccines and the ones still under development, and explore potential risks, benefits and prioritization of vaccination.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: United European Gastroenterol J Year: 2021 Document Type: Article Affiliation country: Ueg2.12103

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: United European Gastroenterol J Year: 2021 Document Type: Article Affiliation country: Ueg2.12103