MRI negative myelopathy post mild SARS-CoV-2 infection: vasculopathy or inflammatory myelitis?
J Neurovirol
; 27(4): 650-655, 2021 08.
Article
in English
| MEDLINE | ID: covidwho-1260617
ABSTRACT
Since the onset of the COVID-19 pandemic, there have been rare reports of spinal cord pathology diagnosed as inflammatory myelopathy and suspected spinal cord ischemia after SARS-CoV-2 infection. Herein, we report five cases of clinical myelopathy and myeloradiculopathy in the setting of post-COVID-19 disease, which were all radiographically negative. Unlike prior reports which typically characterized hospitalized patients with severe COVID-19 disease and critical illness, these patients typically had asymptomatic or mild-moderate COVID-19 disease and lacked radiologic evidence of structural spinal cord abnormality. This case series highlights that COVID-19 associated myelopathy is not rare, requires a high degree of clinical suspicion as imaging markers may be negative, and raises several possible pathophysiologic mechanisms.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Spinal Cord Diseases
/
COVID-19
Type of study:
Case report
/
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
J Neurovirol
Journal subject:
Neurology
/
Virology
Year:
2021
Document Type:
Article
Affiliation country:
S13365-021-00986-w
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