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Effect of specific non-pharmaceutical intervention policies on SARS-CoV-2 transmission in the counties of the United States.
Yang, Bingyi; Huang, Angkana T; Garcia-Carreras, Bernardo; Hart, William E; Staid, Andrea; Hitchings, Matt D T; Lee, Elizabeth C; Howe, Chanelle J; Grantz, Kyra H; Wesolowksi, Amy; Lemaitre, Joseph Chadi; Rattigan, Susan; Moreno, Carlos; Borgert, Brooke A; Dale, Celeste; Quigley, Nicole; Cummings, Andrew; McLorg, Alizée; LoMonaco, Kaelene; Schlossberg, Sarah; Barron-Kraus, Drew; Shrock, Harrison; Lessler, Justin; Laird, Carl D; Cummings, Derek A T.
  • Yang B; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Huang AT; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Garcia-Carreras B; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Hart WE; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Staid A; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Hitchings MDT; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Lee EC; Sandia National Laboratories, Albuquerque, NM, USA.
  • Howe CJ; Sandia National Laboratories, Albuquerque, NM, USA.
  • Grantz KH; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Wesolowksi A; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Lemaitre JC; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Rattigan S; Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
  • Moreno C; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Borgert BA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Dale C; Department of Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Quigley N; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Cummings A; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • McLorg A; Department of Biology, University of Florida, Gainesville, FL, USA.
  • LoMonaco K; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Schlossberg S; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Barron-Kraus D; Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
  • Shrock H; Department of Biology, University of Florida, Gainesville, FL, USA.
  • Lessler J; Department of Mathematics, Syracuse University, Syracuse, NY, USA.
  • Laird CD; Department of Public Health, Syracuse University, Syracuse, NY, USA.
  • Cummings DAT; Department of Biology, University of Florida, Gainesville, FL, USA.
Nat Commun ; 12(1): 3560, 2021 06 11.
Article in English | MEDLINE | ID: covidwho-1265953
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ABSTRACT
Non-pharmaceutical interventions (NPIs) remain the only widely available tool for controlling the ongoing SARS-CoV-2 pandemic. We estimated weekly values of the effective basic reproductive number (Reff) using a mechanistic metapopulation model and associated these with county-level characteristics and NPIs in the United States (US). Interventions that included school and leisure activities closure and nursing home visiting bans were all associated with a median Reff below 1 when combined with either stay at home orders (median Reff 0.97, 95% confidence interval (CI) 0.58-1.39) or face masks (median Reff 0.97, 95% CI 0.58-1.39). While direct causal effects of interventions remain unclear, our results suggest that relaxation of some NPIs will need to be counterbalanced by continuation and/or implementation of others.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Infection Control / COVID-19 / Health Policy Type of study: Experimental Studies / Observational study / Prognostic study Limits: Humans Country/Region as subject: North America Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2021 Document Type: Article Affiliation country: S41467-021-23865-8

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Infection Control / COVID-19 / Health Policy Type of study: Experimental Studies / Observational study / Prognostic study Limits: Humans Country/Region as subject: North America Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2021 Document Type: Article Affiliation country: S41467-021-23865-8