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COVID-19 Vaccination-Associated Lymphadenopathy on FDG PET/CT: Distinctive Features in Adenovirus-Vectored Vaccine.
Shin, Muheon; Hyun, Chae Young; Choi, Yoon Ho; Choi, Joon Young; Lee, Kyung-Han; Cho, Young Seok.
  • Shin M; From the Department of Nuclear Medicine.
  • Hyun CY; From the Department of Nuclear Medicine.
  • Choi YH; Center for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Choi JY; From the Department of Nuclear Medicine.
  • Lee KH; From the Department of Nuclear Medicine.
  • Cho YS; From the Department of Nuclear Medicine.
Clin Nucl Med ; 46(10): 814-819, 2021 Oct 01.
Article in English | MEDLINE | ID: covidwho-1266240
ABSTRACT

PURPOSE:

This study investigated 18F-FDG PET/CT features of adenovirus-vectored vaccination against COVID-19 in healthy subjects. PATIENTS AND

METHODS:

Thirty-one health care workers had been vaccinated Vaxzevria and underwent FDG PET/CT as an optional test for a cancer screening program. Size and FDG uptake of the hypermetabolic lymph nodes were measured. Uptake value of spleen was also measured with liver for comparison.

RESULTS:

All examinees who underwent FDG PET/CT within 14 days' interval showed hypermetabolic lymphadenopathies ipsilateral to vaccine injection. All examinees with hypermetabolic lymphadenopathy had simultaneous muscular uptakes until 23 days' interval. Among 12 examinees who underwent FDG PET/CT more than 15 days after vaccination, only 3 male examinees did not show hypermetabolism in the axillary lymph nodes. There was no female examinee with negative hypermetabolic lymphadenopathy until 29 days after vaccination.

CONCLUSIONS:

Hypermetabolic reactive lymphadenopathy in the ipsilateral axillary area with or without supraclavicular area is most likely to occur in a healthy person with recent adenovirus-vectored COVID-19 vaccination on FDG PET/CT.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Adenovirus Vaccines / Lymphadenopathy / COVID-19 Type of study: Diagnostic study Topics: Vaccines / Variants Limits: Humans / Male Language: English Journal: Clin Nucl Med Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Adenovirus Vaccines / Lymphadenopathy / COVID-19 Type of study: Diagnostic study Topics: Vaccines / Variants Limits: Humans / Male Language: English Journal: Clin Nucl Med Year: 2021 Document Type: Article