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Unusual source of recurrent Corynebacterium bacteraemia in an immunocompromised patient.
Bakhsh, Abdul Rahim Ali; Lewis, Keir Edward.
  • Bakhsh ARA; General Medicine, Prince Philip Hospital, Llanelli, UK arahimab@gmail.com.
  • Lewis KE; Respiratory Medicine, Prince Philip Hospital, Llanelli, UK.
BMJ Case Rep ; 14(6)2021 Jun 11.
Article in English | MEDLINE | ID: covidwho-1266368
ABSTRACT
We describe a unique case of a patient with acute myeloid leukaemia (AML), with recurring infections during chemotherapy from chronic nasal carriage of non-diphtherial Corynebacterium, who was eventually diagnosed as she presented with neutropaenic sepsis. Identifying (often multiple) sources of infection in immunocompromised patients is crucial but deciding whether multiple organisms, which in health are considered as commensals, are actually pathogenic during vulnerable states-can be clinically difficult. Our case highlights the efforts to correctly identify the actual source of this rare organism and the recognition of its pathogenic potential when other illnesses present. We also review the literature of Corynebacteria in patients with haematological malignancies but believe this is the first case of AML to be infected with Corynebacterium presenting during the COVID-19 pandemic with a probable incidental positive swab for SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bacteremia / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Limits: Female / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-242560

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bacteremia / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Limits: Female / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-242560