Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19.
Regen Med
; 16(6): 525-533, 2021 06.
Article
in English
| MEDLINE | ID: covidwho-1266635
ABSTRACT
Aim:
There is a critical need for safe and effective treatments for COVID-19. One possible type of treatment is cellular medicine such as stem cell therapy, but its potential is unclear. Here, our aim was to assess the potential impact of the many cellular medicine trials for COVID-19. Materials &methods:
We collected and analyzed data for defined criteria from trial registries.Results:
Our data suggest that relatively few of these COVID-19 trials will produce high-level evidence, but that on average they may be somewhat more rigorous than typical cell therapy trials unrelated to COVID-19.Conclusion:
Most COVID-19 cellular medicine trials have relatively low potential for rapid, concrete impact. We discuss the findings in the context of the cellular medicine field overall.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Stem Cells
/
Stem Cell Transplantation
/
SARS-CoV-2
/
COVID-19
Type of study:
Experimental Studies
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Language:
English
Journal:
Regen Med
Year:
2021
Document Type:
Article
Affiliation country:
Rme-2021-0025
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