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Case series of four secondary mucormycosis infections in COVID-19 patients, the Netherlands, December 2020 to May 2021.
Buil, Jochem B; van Zanten, Arthur R H; Bentvelsen, Robbert G; Rijpstra, Tom A; Goorhuis, Bram; van der Voort, Sanne; Wammes, Linda J; Janson, Jeroen A; Melchers, Max; Heusinkveld, Moniek; Melchers, Willem J G; Kuijper, Ed J; Verweij, Paul E.
  • Buil JB; Department of Medical Microbiology, Radboud University Medical Center, and Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, the Netherlands.
  • van Zanten ARH; Department of Intensive Care, Gelderse Vallei Hospital, Ede, the Netherlands.
  • Bentvelsen RG; Microvida Laboratory for Microbiology, Amphia Hospital, Breda, the Netherlands.
  • Rijpstra TA; Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Goorhuis B; Department of Intensive Care, Amphia Hospital, Breda, the Netherlands.
  • van der Voort S; Department of Infectious Diseases, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Wammes LJ; Department of Infectious Diseases, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Janson JA; Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Melchers M; Department of Intensive Care, Leiden University Medical Center, Leiden, the Netherlands.
  • Heusinkveld M; Department of Intensive Care, Gelderse Vallei Hospital, Ede, the Netherlands.
  • Melchers WJG; Department of Medical Microbiology, Gelderse Vallei Hospital, Ede, the Netherlands.
  • Kuijper EJ; Department of Medical Microbiology, Radboud University Medical Center, and Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, the Netherlands.
  • Verweij PE; Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands.
Euro Surveill ; 26(23)2021 06.
Article in English | MEDLINE | ID: covidwho-1266639
ABSTRACT
We describe four secondary fungal infections caused by Mucorales species in COVID-19 patients. Three COVID-19 associated mucormycosis (CAM) occurred in ICU, one outside ICU. All were men aged > 50 years, three died. Clinical presentations included pulmonary, rhino-orbital cerebral and disseminated infection. Infections occurred in patients with and without diabetes mellitus. CAM is an emerging disease and our observations underscore the need to be aware of invasive mucormycosis, including in COVID-19 patients without (poorly controlled) diabetes mellitus and outside ICU.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Mucorales / Mucormycosis Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Female / Humans / Male Country/Region as subject: Europa Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: 1560-7917.ES.2021.26.23.2100510

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Mucorales / Mucormycosis Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Female / Humans / Male Country/Region as subject: Europa Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: 1560-7917.ES.2021.26.23.2100510