The Notch Pathway: A Link Between COVID-19 Pathophysiology and Its Cardiovascular Complications.
Front Cardiovasc Med
; 8: 681948, 2021.
Article
in English
| MEDLINE | ID: covidwho-1266657
ABSTRACT
COVID-19 is associated with a large number of cardiovascular sequelae, including dysrhythmias, myocardial injury, myocarditis and thrombosis. The Notch pathway is one likely culprit leading to these complications due to its direct role in viral entry, inflammation and coagulation processes, all shown to be key parts of COVID-19 pathogenesis. This review highlights links between the pathophysiology of SARS-CoV2 and the Notch signaling pathway that serve as primary drivers of the cardiovascular complications seen in COVID-19 patients.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Topics:
Long Covid
Language:
English
Journal:
Front Cardiovasc Med
Year:
2021
Document Type:
Article
Affiliation country:
Fcvm.2021.681948
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