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Unilateral Optic Neuritis Associated with SARS-CoV-2 Infection: A Rare Complication.
Deane, Kitson; Sarfraz, Azza; Sarfraz, Zouina; Valentine, Dhiviyan; Idowu, Abidemi Rachael; Sanchez, Vincent.
  • Deane K; Department of Medicine, Woodhull Medical Center, New York City, NY, USA.
  • Sarfraz A; Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
  • Sarfraz Z; Department of Medicine, Fatima Jinnah Medical University, Lahore, Pakistan.
  • Valentine D; Department of Medicine, Woodhull Medical Center, New York City, NY, USA.
  • Idowu AR; Department of Medicine, Woodhull Medical Center, New York City, NY, USA.
  • Sanchez V; Department of Medicine, St. George's University School of Medicine, St. Georges, Grenada.
Am J Case Rep ; 22: e931665, 2021 Jun 13.
Article in English | MEDLINE | ID: covidwho-1266947
ABSTRACT
BACKGROUND Since the outbreak of the SARS-CoV-2 infection, extensive research has been conducted on the pulmonary implications of this novel disease. However, there has been limited data on the extrapulmonary manifestations. There have been few documented causes of optic involvement and little is understood about the pathophysiology around its presentation and the possible treatments to prevent long-term complications. Here, we describe a case of optic neuritis in a female patient concurrently infected with SARS-CoV-2. Given the plethora of evidence supporting neurological manifestations of the virus, we hypothesize that there is an association between our patient's optic neuritis and her infection with SARS-CoV-2. CASE REPORT A 21-year-old woman with no past medical history who presented with blurry vision in her left eye. Optic neuritis was suspected with physical examination and confirmed with imaging of the optic nerve. Further diagnostic evaluation was nonsuggestive of multiple sclerosis and other demyelinating diseases; however, the patient was found to be positive for SARS-CoV-2. Steroids and remdesivir treatment were started, but without the presence of any respiratory symptoms. The patient's symptoms completely resolved by day 5 of hospitalization and she was discharged home without any complications. CONCLUSIONS Optic neuritis has remained an uncommon complication of SARS-CoV-2. This rather rare complication of SARS-CoV-2 is one that clinicians should be cognizant of due to the long-term implications of optic neuritis. Furthermore, it is pertinent to consider ophthalmic involvement in SARS-CoV-2 infection to appropriately guide patient care during the pandemic, as prompt treatment can lead to improved outcomes.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Optic Neuritis / COVID-19 / Multiple Sclerosis Type of study: Case report / Diagnostic study / Experimental Studies / Prognostic study Topics: Long Covid Limits: Adult / Female / Humans / Young adult Language: English Journal: Am J Case Rep Year: 2021 Document Type: Article Affiliation country: Ajcr.931665

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Optic Neuritis / COVID-19 / Multiple Sclerosis Type of study: Case report / Diagnostic study / Experimental Studies / Prognostic study Topics: Long Covid Limits: Adult / Female / Humans / Young adult Language: English Journal: Am J Case Rep Year: 2021 Document Type: Article Affiliation country: Ajcr.931665