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Coagulation and wound repair during COVID-19.
Menachery, Vineet D; Gralinski, Lisa E.
  • Menachery VD; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas; World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston Texas; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas. Electronic address: Vimenach@utmb.edu.
  • Gralinski LE; Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina. Electronic address: lgralins@email.unc.edu.
J Heart Lung Transplant ; 40(10): 1076-1081, 2021 10.
Article in English | MEDLINE | ID: covidwho-1267682
ABSTRACT
While COVID-19 is best known as a respiratory infection, SARS-CoV-2 causes systemic disease manifestations including coagulopathies. Both dysregulated extracellular matrix remodeling pathways and circulating coagulation proteins are hallmarks of severe COVID-19 and often continue after the resolution of acute infection. Coagulation proteins have proven effective as biomarkers for severe disease and anticoagulants are a mainstay of COVID-19 therapeutics in hospitalized patients. While much knowledge has been gained about the role of clotting pathway activation in COVID-19, much remains to be elucidated in this complex network of signaling pathways.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Wound Healing / Blood Coagulation Disorders / COVID-19 Topics: Long Covid Limits: Humans Language: English Journal: J Heart Lung Transplant Journal subject: Cardiology / Transplantation Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Wound Healing / Blood Coagulation Disorders / COVID-19 Topics: Long Covid Limits: Humans Language: English Journal: J Heart Lung Transplant Journal subject: Cardiology / Transplantation Year: 2021 Document Type: Article