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Lower nasopharyngeal viral loads in pediatric population. The missing piece to understand SARS-CoV-2 infection in children?
Cendejas-Bueno, Emilio; Romero-Gómez, María P; Escosa-García, Luis; Jiménez-Rodríguez, Sonia; Mingorance, Jesús; García-Rodríguez, Julio.
  • Cendejas-Bueno E; Servicio de Microbiología y Parasitología, Hospital Universitario La Paz - IdiPaz, Madrid, Spain. Electronic address: ecendejas77@gmail.com.
  • Romero-Gómez MP; Servicio de Microbiología y Parasitología, Hospital Universitario La Paz - IdiPaz, Madrid, Spain.
  • Escosa-García L; Servicio de Pediatría Hospitalaria, Enfermedades Infecciosas y Tropicales, Hospital Universitario La Paz, Madrid. RITIP (Red de Investigación Translacional en Infectología Pediátrica), Spain.
  • Jiménez-Rodríguez S; Servicio de Microbiología y Parasitología, Hospital Universitario La Paz - IdiPaz, Madrid, Spain.
  • Mingorance J; Servicio de Microbiología y Parasitología, Hospital Universitario La Paz - IdiPaz, Madrid, Spain.
  • García-Rodríguez J; Servicio de Microbiología y Parasitología, Hospital Universitario La Paz - IdiPaz, Madrid, Spain.
J Infect ; 83(2): e18-e19, 2021 08.
Article in English | MEDLINE | ID: covidwho-1267754
ABSTRACT
SARS-CoV-2 virus infects children but, contrary to other respiratory viruses, children tend to be asymptomatic or to have less symptoms than adults and are rarely the index case in household transmission chains. The aim of this study was to compare the relative viral loads in nasopharyngeal samples from children aged 0 to 17 years with those of an adult population. We selected 126 positive nasopharyngeal samples from children. Relative viral loads were measured by RT-PCR and the comparative ∆Ct method using primers and probes targeting the viral gene E and the human RNAseP. Relative viral loads were significantly lower in the children population than in the adult one.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study Limits: Adult / Child / Humans Language: English Journal: J Infect Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study Limits: Adult / Child / Humans Language: English Journal: J Infect Year: 2021 Document Type: Article