Topical interferon in recurrent inflammatory macular edema following a cat bite.
Eur J Ophthalmol
; 32(6): NP32-NP35, 2022 Nov.
Article
in English
| MEDLINE | ID: covidwho-1268183
ABSTRACT
INTRODUCTION:
Treating chronic macular edema (CME) post endophthalmitis is a challenge. Use of steroids may reactivate the infection and repeated intravitreal therapy with anti-vascular growth factor inhibitors (Anti-VEGF) puts the patient again at the risk of exacerbation of inflammation or endophthalmitis. We describe a case of CME post traumatic endophthalmitis successfully treated with topical interferon therapy. CASE DESCRIPTION A 34-year-old Asian Indian lady with a history of cat bite to her right eye and treated elsewhere as traumatic endophthalmitis with recurrent macular edema, presented to us 1 year after the injury. She had received anti-VEGF injection for same. Her medical history was non-contributory except for close contact with her cat. Therapeutic trials with oral doxycycline followed by oral albendazole with steroids, as well as repeated anti-VEGF therapy failed to prevent recurrence of CME. Patient's steroid responsiveness and reluctance for injections, made us to opt for a novel topical Interferon therapy. Macular edema resolved in 2 months. Interruption of interferon therapy due to COVID-lock down resulted in recurrence of the CME, which again responded well to interferon monotherapy.CONCLUSION:
Topical interferon may have a role in the treatment of inflammatory macular edema and can serve as a, safer, economical and non-invasive treatment option compared to intravitreal steroids and anti-VEGFs.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Macular Edema
/
Endophthalmitis
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Eur J Ophthalmol
Journal subject:
Ophthalmology
Year:
2022
Document Type:
Article
Affiliation country:
11206721211024809
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