Your browser doesn't support javascript.
An Illustrated Guide to the Imaging Evolution of COVID in Non-Epidemic Areas of Southeast China.
Wang, Lihua; Jiaerken, Yeerfan; Li, Qian; Huang, Peiyu; Shen, Zhujing; Zhao, Tongtong; Zheng, Hanpeng; Ji, Wenbin; Gao, Yuantong; Xia, Junli; Cheng, Jianmin; Ma, Jianbing; Liu, Jun; Liu, Yongqiang; Su, Miaoguang; Ruan, Guixiang; Shu, Jiner; Ren, Dawei; Zhao, Zhenhua; Yao, Weigen; Yang, Yunjun; Zhang, Minming.
  • Wang L; Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Jiaerken Y; Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Li Q; Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Huang P; Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Shen Z; Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Zhao T; Fuyang Second People's Hospital, Fuyang, China.
  • Zheng H; Yueqing People's Hospital, Yueqing, China.
  • Ji W; Zhejiang Taizhou Hospital, Taizhou, China.
  • Gao Y; Radiology Department, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
  • Xia J; Bozhou Bone Trauma Hospital Image Center, Bozhou, China.
  • Cheng J; Department of Radiology, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
  • Ma J; First Hospital of Jiaxing, Jiaxing, China.
  • Liu J; Second Xiangya Hospital, Central South University, Changsha, China.
  • Liu Y; Quzhou Kecheng People's Hospital, Quzhou, China.
  • Su M; Pingyang County People's Hospital, Wenzhou, China.
  • Ruan G; Yuhang First People's Hospital, Hangzhou, China.
  • Shu J; Jinhua Central Hospital, Jinhua, China.
  • Ren D; Ningbo First Hospital, Ningbo, China.
  • Zhao Z; Shaoxing People's Hospital, Shaoxing, China.
  • Yao W; Yuyao People's Hospital, Yuyao, China.
  • Yang Y; Radiology Department, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
  • Zhang M; Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Front Mol Biosci ; 8: 648180, 2021.
Article in English | MEDLINE | ID: covidwho-1268265
ABSTRACT

Purpose:

By analyzing the CT manifestations and evolution of COVID in non-epidemic areas of southeast China, analyzing the developmental abnormalities and accompanying signs in the early and late stages of the disease, providing imaging evidence for clinical diagnosis and identification, and assisting in judging disease progression and monitoring prognosis.

Methods:

This retrospective and multicenter study included 1,648 chest CT examinations from 693 patients with laboratory-confirmed COVID-19 infection from 16 hospitals of southeast China between January 19 and March 27, 2020. Six trained radiologists analyzed and recorded the distribution and location of the lesions in the CT images of these patients. The accompanying signs include crazy-paving sign, bronchial wall thickening, microvascular thickening, bronchogram sign, fibrous lesions, halo and reverse-halo signs, nodules, atelectasis, and pleural effusion, and at the same time, they analyze the evolution of the abovementioned manifestations over time.

Result:

There were 1,500 positive findings in 1,648 CT examinations of 693 patients; the average age of the patients was 46 years, including 13 children; the proportion of women was 49%. Early CT manifestations are single or multiple nodular, patchy, or flaky ground-glass-like density shadows. The frequency of occurrence of ground-glass shadows (47.27%), fibrous lesions (42.60%), and microvascular thickening (40.60%) was significantly higher than that of other signs. Ground-glass shadows increase and expand 3-7 days after the onset of symptoms. The distribution and location of lesions were not significantly related to the appearance time. Ground-glass shadow is the most common lesion, with an average absorption time of 6.2 days, followed by consolidation, with an absorption time of about 6.3 days. It takes about 8 days for pure ground-glass lesions to absorb. Consolidation change into ground glass or pure ground glass takes 10-14 days. For ground-glass opacity to evolve into pure ground-glass lesions, it takes an average of 17 days. For ground-glass lesions to evolve into consolidation, it takes 7 days, pure ground-glass lesions need 8 days to evolve into ground-glass lesions. The average time for CT signs to improve is 10-15 days, and the first to improve is the crazy-paving sign and nodules; while the progression of the disease is 6-12 days, the earliest signs of progression are air bronchogram signs, bronchial wall thickening, and bronchiectasis. There is no severe patient in this study.

Conclusion:

This study depicts the CT manifestation and evolution of COVID in non-epidemic origin areas, and provides valuable first-hand information for clinical diagnosis and judgment of patient's disease evolution and prediction.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Language: English Journal: Front Mol Biosci Year: 2021 Document Type: Article Affiliation country: Fmolb.2021.648180

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Language: English Journal: Front Mol Biosci Year: 2021 Document Type: Article Affiliation country: Fmolb.2021.648180