A Systematic Review of the Costs Relating to Non-pharmaceutical Interventions Against Infectious Disease Outbreaks.
Appl Health Econ Health Policy
; 19(5): 673-697, 2021 09.
Article
in English
| MEDLINE | ID: covidwho-1269032
ABSTRACT
BACKGROUND:
Non-pharmaceutical interventions (NPIs) are the cornerstone of infectious disease outbreak response in the absence of effective pharmaceutical interventions. Outbreak strategies often involve combinations of NPIs that may change according to disease prevalence and population response. Little is known with regard to how costly each NPI is to implement. This information is essential to inform policy decisions for outbreak response.OBJECTIVE:
To address this gap in existing literature, we conducted a systematic review on outbreak costings and simulation studies related to a number of NPI strategies, including isolating infected individuals, contact tracing and quarantine, and school closures.METHODS:
Our search covered the MEDLINE and EMBASE databases, studies published between 1990 and 24 March 2020 were included. We included studies containing cost data for our NPIs of interest in pandemic, epidemic, and outbreak response scenarios.RESULTS:
We identified 61 relevant studies. There was substantial heterogeneity in the cost components recorded for NPIs in outbreak costing studies. The direct costs of NPIs for which costing studies existed also ranged widely isolating infected individuals per case US$141.18 to US$1042.68 (2020 values), tracing and quarantine of contacts per contact US$40.73 to US$93.59, social distancing US$33.76 to US$167.92, personal protection and hygiene US$0.15 to US$895.60.CONCLUSION:
While there are gaps and heterogeneity in available cost data, the findings of this review and the collated cost database serve as an important resource for evidence-based decision-making for estimating costs pertaining to NPI implementation in future outbreak response policies.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Reviews
/
Systematic review/Meta Analysis
Limits:
Humans
Language:
English
Journal:
Appl Health Econ Health Policy
Journal subject:
Public Health
/
Health Services
Year:
2021
Document Type:
Article
Affiliation country:
S40258-021-00659-z
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