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Electrocardiography on admission is associated with poor outcomes in coronavirus disease 2019 (COVID-19) patients: A systematic review and meta-analysis.
Alsagaff, Mochamad Yusuf; Oktaviono, Yudi Her; Dharmadjati, Budi Baktijasa; Lefi, Achmad; Al-Farabi, Makhyan Jibril; Gandi, Parama; Marsudi, Bagas Adhimurda; Azmi, Yusuf.
  • Alsagaff MY; Department of Cardiology and Vascular Medicine Faculty of Medicine Soetomo General Hospital Universitas Airlangga Surabaya Indonesia.
  • Oktaviono YH; Department of Cardiology and Vascular Medicine Faculty of Medicine Soetomo General Hospital Universitas Airlangga Surabaya Indonesia.
  • Dharmadjati BB; Department of Cardiology and Vascular Medicine Faculty of Medicine Soetomo General Hospital Universitas Airlangga Surabaya Indonesia.
  • Lefi A; Department of Cardiology and Vascular Medicine Faculty of Medicine Soetomo General Hospital Universitas Airlangga Surabaya Indonesia.
  • Al-Farabi MJ; Department of Cardiology and Vascular Medicine Faculty of Medicine Soetomo General Hospital Universitas Airlangga Surabaya Indonesia.
  • Gandi P; Department of Cardiology and Vascular Medicine Faculty of Medicine Soetomo General Hospital Universitas Airlangga Surabaya Indonesia.
  • Marsudi BA; Department of Cardiology and Vascular Medicine Faculty of Medicine Harapan Kita National Heart Center Universitas Indonesia Jakarta Indonesia.
  • Azmi Y; Faculty of Medicine Universitas Airlangga Surabaya Indonesia.
J Arrhythm ; 37(4): 877-885, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-1269116
ABSTRACT

BACKGROUND:

Electrocardiogram (ECG) is a widely accessible diagnostic tool that can easily be obtained on admission and can reduce excessive contact with coronavirus disease 2019 (COVID-19) patients. A systematic review and meta-analysis were performed to evaluate the latest evidence on the association of ECG on admission and the poor outcomes in COVID-19.

METHODS:

A literature search was conducted on online databases for observational studies evaluating ECG parameters and composite poor outcomes comprising ICU admission, severe illness, and mortality in COVID-19 patients.

RESULTS:

A total of 2,539 patients from seven studies were included in this analysis. Pooled analysis showed that a longer corrected QT (QTc) interval and more frequent prolonged QTc interval were associated with composite poor outcome ([WMD 6.04 [2.62-9.45], P = .001; I 20%] and [RR 1.89 [1.52-2.36], P < .001; I 217%], respectively). Patients with poor outcome had a longer QRS duration and a faster heart rate compared with patients with good outcome ([WMD 2.03 [0.20-3.87], P = .030; I 246.1%] and [WMD 5.96 [0.96-10.95], P = .019; I 255.9%], respectively). The incidence of left bundle branch block (LBBB), premature atrial contraction (PAC), and premature ventricular contraction (PVC) were higher in patients with poor outcome ([RR 2.55 [1.19-5.47], P = .016; I 265.9%]; [RR 1.94 [1.32-2.86], P = .001; I 262.8%]; and [RR 1.84 [1.075-3.17], P = .026; I 270.6%], respectively). T-wave inversion and ST-depression were more frequent in patients with poor outcome ([RR 1.68 [1.31-2.15], P < .001; I 214.3%] and [RR 1.61 [1.31-2.00], P < .001; I 249.5%], respectively).

CONCLUSION:

Most ECG abnormalities on admission are significantly associated with an increased composite poor outcome in patients with COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Language: English Journal: J Arrhythm Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Language: English Journal: J Arrhythm Year: 2021 Document Type: Article