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At a crossroads: coronavirus disease 2019 recovery and the risk of pulmonary vascular disease.
Cascino, Thomas M; Desai, Ankit A; Kanthi, Yogendra.
  • Cascino TM; Frankel Cardiovascular Center, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
  • Desai AA; Department of Medicine, Indiana University, Indianapolis, Indiana.
  • Kanthi Y; Frankel Cardiovascular Center, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
Curr Opin Pulm Med ; 27(5): 342-349, 2021 09 01.
Article in English | MEDLINE | ID: covidwho-1269618
ABSTRACT
PURPOSE OF REVIEW The coronavirus disease 2019 (COVID-19) pandemic has led to almost 3,000,000 deaths across 139 million people infected worldwide. Involvement of the pulmonary vasculature is considered a major driving force for morbidity and mortality. We set out to summarize current knowledge on the acute manifestations of pulmonary vascular disease (PVD) resulting from COVID-19 and prioritize long-term complications that may result in pulmonary hypertension (PH). RECENT

FINDINGS:

Acute COVID-19 infection can result in widespread involvement of the pulmonary vasculature, myocardial injury, evidence of persistent lung disease, and venous thromboembolism. Post COVID-19 survivors frequently report ongoing symptoms and may be at risk for the spectrum of PH, including group 1 pulmonary arterial hypertension, group 2 PH due to left heart disease, group 3 PH due to lung disease and/or hypoxia, and group 4 chronic thromboembolic PH.

SUMMARY:

The impact of COVID-19 on the pulmonary vasculature is central to determining disease severity. Although the long-term PVD manifestations of COVID-19 are currently uncertain, optimizing the care of risk factors for PH and monitoring for the development of PVD will be critical to reducing long-term morbidity and improving the health of survivors.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Vascular Diseases / COVID-19 / Lung Diseases Type of study: Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Curr Opin Pulm Med Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vascular Diseases / COVID-19 / Lung Diseases Type of study: Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Curr Opin Pulm Med Year: 2021 Document Type: Article