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Multisystem Inflammatory Syndrome in Children During Induction Chemotherapy in a Newly Diagnosed Pediatric Acute Myeloid Leukemia and Concurrent COVID-19.
Tekle-Yohannes, Girmay H; Mann, Esther; Miller, Michal A.
  • Tekle-Yohannes GH; Departments of Pediatric Hematology and Oncology.
  • Mann E; Pediatrics, Janet Weis Children's Hospital, Danville, PA.
  • Miller MA; Departments of Pediatric Hematology and Oncology.
J Pediatr Hematol Oncol ; 44(2): e532-e536, 2022 03 01.
Article in English | MEDLINE | ID: covidwho-1270768
ABSTRACT
A 15-year-old male presented with fatigue and weight loss for 1 month, petechiae and bruising for 2 weeks. He was diagnosed with concurrent new acute myeloid leukemia and coronavirus disease 2019. He was febrile and chest computed tomography scan showed ground glass opacities. Fever resolved after 4 days. Polymerase chain reaction test for coronavirus disease 2019 became negative after 2 days. Induction chemotherapy was initiated on day 8 and was complicated by multisystem inflammatory syndrome in children. The multisystem inflammatory syndrome in children was managed with symptomatic treatment and continued chemotherapy. Patient recovered and end of induction bone marrow showed remission of the leukemia.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Systemic Inflammatory Response Syndrome / Induction Chemotherapy / SARS-CoV-2 / COVID-19 Type of study: Case report Topics: Long Covid Limits: Adolescent / Humans / Male Language: English Journal: J Pediatr Hematol Oncol Journal subject: Hematology / Neoplasms / Pediatrics Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Systemic Inflammatory Response Syndrome / Induction Chemotherapy / SARS-CoV-2 / COVID-19 Type of study: Case report Topics: Long Covid Limits: Adolescent / Humans / Male Language: English Journal: J Pediatr Hematol Oncol Journal subject: Hematology / Neoplasms / Pediatrics Year: 2022 Document Type: Article