COVID-19 and Candida duobushaemulonii superinfection: A case report.
J Mycol Med
; 31(3): 101168, 2021 Sep.
Article
in English
| MEDLINE | ID: covidwho-1272630
ABSTRACT
INTRODUCTION:
Critically ill COVID-19 patients are at high risk for nosocomial bacterial and fungal infections due to several predisposing factors such as intensive care unit stay, mechanical ventilation, and broad-spectrum antibiotics. Data regarding multidrug resistant (MDR) Candida species in COVID-19 patients is scarce, and nonexistent regarding Candida duobushaemulonii superinfections. CASE DESCRIPTION A 34-year-old male presented to our institution with acute respiratory distress syndrome (ARDS) due to COVID-19 infection and developed Candida duobushaemulonii fungemia after multiple courses of antibiotics and prolonged mechanical ventilation. He died after recurrent pneumothorax led to respiratory failure and cardiac arrest.DISCUSSION:
Bacterial and fungal infections are common complications of viral pneumonia in critically ill patients. Data regarding these infections in COVID-19 patients has been poorly studied with only a few cases reporting secondary infection, mostly without identifying specific pathogens. Prolonged hospital stays, invasive interventions (central venous catheter, mechanical ventilation), and the use of broad-spectrum antibiotics in COVID-19 infections could carry a high risk of bacterial and/or fungal superinfections.CONCLUSION:
Strategies to improve outcome in COVID-19 ICU patients should include early recognition of candidemia and appropriate antifungal therapy.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Superinfection
/
Candidemia
/
COVID-19
Type of study:
Case report
/
Etiology study
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
J Mycol Med
Year:
2021
Document Type:
Article
Affiliation country:
J.mycmed.2021.101168
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