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Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2.
Drózdz, Mateusz; Krzyzek, Pawel; Dudek, Barbara; Makuch, Sebastian; Janczura, Adriana; Paluch, Emil.
  • Drózdz M; Laboratory of RNA Biochemistry, Institute of Chemistry and Biochemistry, Freie Universität Berlin, Takustraße 6, 14195 Berlin, Germany.
  • Krzyzek P; Department of Microbiology, Wroclaw Medical University, St. T. Chalubinskiego 4, 50-376 Wroclaw, Poland.
  • Dudek B; Laboratory of Microbiology, Private Health Care Institution, St. Jana Pawla II, 41-100 Siemianowice Slaskie, Poland.
  • Makuch S; Department of Pathology, Wroclaw Medical University, St. K. Marcinkowskiego 1, 50-368 Wroclaw, Poland.
  • Janczura A; Department of Microbiology, Wroclaw Medical University, St. T. Chalubinskiego 4, 50-376 Wroclaw, Poland.
  • Paluch E; Department of Microbiology, Wroclaw Medical University, St. T. Chalubinskiego 4, 50-376 Wroclaw, Poland.
Viruses ; 13(6)2021 06 16.
Article in English | MEDLINE | ID: covidwho-1273517
ABSTRACT
Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and transmission to humans are dramatically emerging. Although cases of SARS-CoV-2 infection have been found in pets including dogs, cats, and ferrets, to date there is no strong evidence for pet-to-human transmission or sustained pet-to-pet transmission of SARS-CoV-2. However, an increasing number of studies reporting detection of SARS-CoV-2 in farmed minks raises suspicion of potential viral transmission from these animals to humans. Furthermore, due to the high susceptibility of cats, ferrets, minks and hamsters to COVID-19 infection under natural and/or experimental conditions, these animals have been extensively explored as animal models to study the SARS-CoV-2 pathogenesis and transmission. In this review, we present the latest reports focusing on SARS-CoV-2 detection, isolation, and characterization in pets. Moreover, based on the current literature, we document studies aiming to broaden the knowledge about pathogenicity and transmissibility of SARS-CoV-2, and the development of viral therapeutics, drugs and vaccines. Lastly, considering the high rate of SARS-CoV-2 evolution and replication, we also suggest routes of protection against the virus.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Zoonoses / Pets / SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Animals / Humans Language: English Year: 2021 Document Type: Article Affiliation country: V13061149

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Zoonoses / Pets / SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Animals / Humans Language: English Year: 2021 Document Type: Article Affiliation country: V13061149