Nanocapsule designs for antimicrobial resistance.
Nanoscale
; 13(23): 10342-10355, 2021 Jun 21.
Article
in English
| MEDLINE | ID: covidwho-1274489
ABSTRACT
The pressing need of new antimicrobial products is growing stronger, particularly because of widespread antimicrobial resistance, endangering our ability to treat common infections. The recent coronavirus pandemic has dramatically highlighted the necessity of effective antibacterial and antiviral protection. This work explores at the molecular level the mechanism of action of antibacterial nanocapsules assembled in virus-like particles, their stability and their interaction with mammal and antimicrobial model membranes. We use Molecular Dynamics with force-fields of different granularity and protein design strategies to study the stability, self-assembly and membrane poration properties of these nanocapsules.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Nanocapsules
/
Anti-Infective Agents
Limits:
Animals
Language:
English
Journal:
Nanoscale
Year:
2021
Document Type:
Article
Affiliation country:
D0nr08146a
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