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Angioedema: differential diagnosis and acute management.
Tachdjian, Raffi; Johnston, Douglas T.
  • Tachdjian R; Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Johnston DT; Carolina Asthma & Allergy Center, Charlotte, NC, USA.
Postgrad Med ; 133(7): 765-770, 2021 Sep.
Article in English | MEDLINE | ID: covidwho-1276020
ABSTRACT
A clinical vignette illustrates a typical presentation of a patient seeking help for acute angioedema. Despite the risks of SARS-CoV-2 (COVID-19) exposure, it is critical to evaluate patients with acute angioedema in person, because there is always the potential for angioedema to progress to the head, neck, or lungs, which can rapidly compromise the airways and require immediate intervention to avoid potential asphyxiation. There are three mediators of angioedema, histamine, leukotriene, or bradykinin, each requiring different management. This article provides clinicians essential information for differentiating between these types of angioedema, including an overview of the underlying pathogenies of angioedema, and the subjective and objective findings that are useful in differentiating between angioedema types. The article ends with the appropriate management for each type of acute angioedema, including the medications approved by the FDA for on-demand treatment of an HAE attack.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Angioedema Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: Postgrad Med Year: 2021 Document Type: Article Affiliation country: 00325481.2021.1945219

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Angioedema Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: Postgrad Med Year: 2021 Document Type: Article Affiliation country: 00325481.2021.1945219