Comprehensive Review on Neuro-COVID-19 Pathophysiology and Clinical Consequences.
Neurotox Res
; 39(5): 1613-1629, 2021 Oct.
Article
in English
| MEDLINE | ID: covidwho-1281337
ABSTRACT
Aside from the respiratory distress as the predominant clinical presentation of SARS-CoV-2 infection, various neurological complications have been reported with the infection during the ongoing pandemic, some of which cause serious morbidity and mortality. Herein, we gather the latest anatomical evidence of the virus's presence within the central nervous system. We then delve into the possible SARS-CoV-2 entry routes into the neurological tissues, with the hematogenous and the neuronal routes as the two utmost passage routes into the nervous system. We then give a comprehensive review of the neurological manifestations of the SARS-CoV-2 invasion in both the central and peripheral nervous system and its underlying pathophysiology via investigating large studies in the field and case reports in cases of study scarcity.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Nervous System Diseases
Type of study:
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Neurotox Res
Journal subject:
Neurology
Year:
2021
Document Type:
Article
Affiliation country:
S12640-021-00389-z
Similar
MEDLINE
...
LILACS
LIS