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An evidence that SARS-Cov-2/COVID-19 spike protein (SP) damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner.
Kucia, Magdalena; Ratajczak, Janina; Bujko, Kamila; Adamiak, Mateusz; Ciechanowicz, Andrzej; Chumak, Vira; Brzezniakiewicz-Janus, Katarzyna; Ratajczak, Mariusz Z.
  • Kucia M; Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA. magdalena.kucia@wum.edu.pl.
  • Ratajczak J; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland. magdalena.kucia@wum.edu.pl.
  • Bujko K; Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
  • Adamiak M; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
  • Ciechanowicz A; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
  • Chumak V; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
  • Brzezniakiewicz-Janus K; Department of Regenerative Medicine, Warsaw Medical University, Warsaw, Poland.
  • Ratajczak MZ; Department of Hematology, University of Zielona Gora, Hospital Gorzow Wlkp., Gorzów Wielkopolski, Poland.
Leukemia ; 35(10): 3026-3029, 2021 10.
Article in English | MEDLINE | ID: covidwho-1284684
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Hematopoietic Stem Cells / Inflammasomes / Spike Glycoprotein, Coronavirus / Endothelial Progenitor Cells / Pyroptosis / NLR Family, Pyrin Domain-Containing 3 Protein / Angiotensin-Converting Enzyme 2 Limits: Humans Language: English Journal: Leukemia Journal subject: Hematology / Neoplasms Year: 2021 Document Type: Article Affiliation country: S41375-021-01332-z

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Hematopoietic Stem Cells / Inflammasomes / Spike Glycoprotein, Coronavirus / Endothelial Progenitor Cells / Pyroptosis / NLR Family, Pyrin Domain-Containing 3 Protein / Angiotensin-Converting Enzyme 2 Limits: Humans Language: English Journal: Leukemia Journal subject: Hematology / Neoplasms Year: 2021 Document Type: Article Affiliation country: S41375-021-01332-z