Study on Core prescription of traditional Chinese Medicine for Prevention of viral Respiratory Infectious Diseases based on complex Network

ABSTRACT

Based on the complex network analysis technology, the core drugs and their compatibility rules of traditional Chinese medicine for the prevention of viral respiratory infectious diseases were excavated, and the core prescriptions of traditional Chinese medicine for the prevention of viral respiratory infectious diseases were analyzed. Firstly, the standard database of prescriptions for viral respiratory infectious diseases is constructed by combining the relevant theories of traditional Chinese medicine and database. Secondly, at the micro level, the weighted correlation network of traditional Chinese medicine prescriptions for three typical diseases COVID-19, H1N1 and SARS is constructed, and at the macro level, the weighted correlation network of traditional Chinese medicine prescriptions for viral respiratory infectious diseases is constructed. Then use Python3.6 software to analyze the node strength and compatibility of the data, use Gephi9.2 software to visualize the data, and draw a schematic diagram of complex network data analysis. By using the relevant theoretical knowledge of complex network, statistics and pharmacology, this paper studies and analyzes the weighted association network of traditional Chinese medicine prescriptions of single disease and multiple diseases from the aspects of structure and function. dig out the broad-spectrum core prescription of traditional Chinese medicine for the prevention of viral respiratory infectious diseases, and provide data reference for the active prevention of viral respiratory infectious diseases. So as to provide more scientific ideas and basis for TCM experts in formulating preventive prescriptions for traditional Chinese medicine.