The effect of nitric oxide supplement intake on the value of hematological examination of health workers exposed to covid-19

ABSTRACT

Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chain reaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes, neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an important role in monitoring the course of covid-19 disease Macrophages release nitric oxide (NO) to kill parasites NO inhibits migration and adhesion of leucocytes to the endothelium. Metode The research design used pre-experimental with one group pre-post test, the total sample was 80 health workers who were exposed to Covid-19, the independent variable was the provision of NO and the dependent variable was the result of a hematological examination (leukocytes, lymposites, platelets, neutrophils, hemoglobin and NLR). The intervention was given NO 500 mg mixed with warm water 250 cc, given 3 times a day for 5 days, data analysis used the T-test with a significance value of a<0.05. Results: There is a difference in the results of the pre and post-test hematology giving NO to the results of the examination of leucocytes a=0.001, lymphocytes a=0.000, platelets a=0.000, neutrophils a=0.000, hemoglobin a=0.031, and NLR a=0.000. Conclusion: Giving NO to health workers exposed to Covid-19 can improve the hematology and immune systems to fight the corona virus.