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Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru.
Juscamayta-López, Eduardo; Carhuaricra, Dennis; Tarazona, David; Valdivia, Faviola; Rojas, Nancy; Maturrano, Lenin; Gavilán, Ronnie.
  • Juscamayta-López E; Laboratorio de Infecciones Respiratorias Agudas, Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Peru.
  • Carhuaricra D; Laboratorio de Biología y Genética Molecular, Universidad Nacional Mayor de San Marcos, Lima, Peru.
  • Tarazona D; Laboratorio de Biología y Genética Molecular, Universidad Nacional Mayor de San Marcos, Lima, Peru.
  • Valdivia F; Laboratorio de Infecciones Respiratorias Agudas, Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Peru.
  • Rojas N; Laboratorio de Biología y Genética Molecular, Universidad Nacional Mayor de San Marcos, Lima, Peru.
  • Maturrano L; Laboratorio de Infecciones Respiratorias Agudas, Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Peru.
  • Gavilán R; Laboratorio de Virus Respiratorios, Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Peru.
J Med Virol ; 93(10): 5961-5968, 2021 10.
Article in English | MEDLINE | ID: covidwho-1286127
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ABSTRACT
Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia and a high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: South America / Peru Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.27167

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: South America / Peru Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.27167