The high frequency of anti-PF4/heparin antibodies in patients with COVID-19 is neither related to heparin treatment or to an increased incidence of thrombosis.

Pascreau, Tiffany; Ballester, Marie-Christine; Van Dreden, Patrick; Zia-Chahabi, Sara; Zuber, Benjamin; Choucair, Jad; Bironien, Roselyne; Farfour, Eric; Vasse, Marc

Pascreau, Tiffany; Ballester, Marie-Christine; Van Dreden, Patrick; Zia-Chahabi, Sara; Zuber, Benjamin; Choucair, Jad; Bironien, Roselyne; Farfour, Eric; Vasse, Marc.

Pascreau T; Department of Clinical Biology, Foch Hospital, Suresnes, France.
Ballester MC; INSERM UMR_S 1176, University Paris-Sud, University Paris-Saclay, Le Kremlin-Bicêtre, France.
Van Dreden P; Emergency Unit, Foch hospital, Suresnes, France.
Zia-Chahabi S; R&D, Diagnostica Stago, Gennevilliers, France.
Zuber B; Department of Clinical Biology, Foch Hospital, Suresnes, France.
Choucair J; Department of Medical and Surgical Intensive Care Unit, Foch Hospital, Suresnes, France.
Bironien R; Pneumology Department, Foch Hospital, Suresnes, France.
Farfour E; Department of Clinical Biology, Foch Hospital, Suresnes, France.
Vasse M; Department of Clinical Biology, Foch Hospital, Suresnes, France.

Clin Chem Lab Med ; 59(11): e405-e408, 2021 10 26.

Article in English | MEDLINE | ID: covidwho-1286881

Subject(s)

Antibodies/metabolism; COVID-19 Drug Treatment; Heparin/metabolism; Platelet Factor 4/metabolism; SARS-CoV-2/drug effects; Thrombosis/chemically induced; Aged; Blood Platelets/metabolism; Female; Humans; Immunoglobulin A/metabolism; Immunoglobulin G/metabolism; Immunoglobulin M/metabolism; Incidence; Male; Middle Aged; Thrombosis/metabolism

Keywords

COVID-19; anti-PF4/heparin antibodies; heparin induced thrombocytopenia

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombosis / Platelet Factor 4 / Heparin / SARS-CoV-2 / COVID-19 Drug Treatment / Antibodies Type of study: Observational study Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Clin Chem Lab Med Journal subject: Chemistry, Clinical / Laboratory Techniques and procedures Year: 2021 Document Type: Article Affiliation country: Cclm-2021-0623

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