COVID-19 autopsy cases: detection of virus in endocrine tissues.
J Endocrinol Invest
; 45(1): 209-214, 2022 Jan.
Article
in English
| MEDLINE | ID: covidwho-1287473
ABSTRACT
PURPOSE:
The SARS-CoV-2 genome has been detected in a variety of human samples including blood, urine, semen, and faeces. However, evidence of virus presence in tissues other than lung are limited.METHODS:
We investigated whether SARS-CoV-2 could be detected in 50 autoptic specimens of endocrine organs from 29 patients who died of COVID-19.RESULTS:
The virus was detected in 25 specimens including ten abdominal subcutaneous adipose tissue samples (62%), six testes (67%), and nine thyroid (36%) samples. The analysis of multiple endocrine organ samples obtained from the same patients showed that, in virus-positive cases, the viral genome was consistently detected in all but two matched specimens.CONCLUSION:
Our findings show that the virus spread into endocrine organs is a common event in severe cases. Further studies should assess the rate of the phenomenon in clinically mild cases. The potential long-term effects of COVID-19 on endocrine functions should be taken into consideration.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Endocrine Glands
/
SARS-CoV-2
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
J Endocrinol Invest
Year:
2022
Document Type:
Article
Affiliation country:
S40618-021-01628-y
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