Uncovering Signals from the Coronavirus Genome.
Genes (Basel)
; 12(7)2021 06 25.
Article
in English
| MEDLINE | ID: covidwho-1288842
ABSTRACT
A signal analysis of the complete genome sequenced for coronavirus variants of concern-B.1.1.7 (Alpha), B.1.135 (Beta) and P1 (Gamma)-and coronavirus variants of interest-B.1.429-B.1.427 (Epsilon) and B.1.525 (Eta)-is presented using open GISAID data. We deal with a certain new type of finite alternating sum series having independently distributed terms associated with binary (0,1) indicators for the nucleotide bases. Our method provides additional information to conventional similarity comparisons via alignment methods and Fourier Power Spectrum approaches. It leads to uncover distinctive patterns regarding the intrinsic data organization of complete genomics sequences according to its progression along the nucleotide bases position. The present new method could be useful for the bioinformatics surveillance and dynamics of coronavirus genome variants.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Viral Proteins
/
Genome, Viral
/
Computational Biology
/
SARS-CoV-2
Topics:
Variants
Limits:
Humans
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Genes12070973
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