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A Case of COVID-19 Pregnancy Complicated with Hydrops Fetalis and Intrauterine Death.
Popescu, Daniela Eugenia; Cioca, Andreea; Muresan, Cezara; Navolan, Dan; Gui, Arina; Pop, Ovidiu; Marcovici, Tamara; Ilie, Constantin; Craina, Marius; Boia, Marioara.
  • Popescu DE; Department of Neonatology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No.2, 300041 Timisoara, Romania.
  • Cioca A; Department of Neonatology, Premiere Hospital, Regina Maria Health Network, Calea Aradului, No.113, 300645 Timisoara, Romania.
  • Muresan C; Department of Pathology, Premiere Hospital, Regina Maria Health Network, Calea Aradului, No.113, 300645 Timisoara, Romania.
  • Navolan D; Department of Obstetrics and Gynecology, Premiere Hospital, Regina Maria Health Network, Calea Aradului, No.113, 300645 Timisoara, Romania.
  • Gui A; Department of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No.2, 300041 Timisoara, Romania.
  • Pop O; Department of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No.2, 300041 Timisoara, Romania.
  • Marcovici T; Department of Obstetrics and Gynecology, Premiere Hospital, Regina Maria Health Network, Calea Aradului, No.113, 300645 Timisoara, Romania.
  • Ilie C; Department of Morphological Sciences, University of Oradea, Universitatii Street, No.1, 410087 Oradea, Romania.
  • Craina M; Department of Pediatrics, First Pediatric Clinic, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No.2, 300041 Timisoara, Romania.
  • Boia M; Department of Neonatology, Regina Maria Health Network, Aristide Demetriade Street, No.1, 300088 Timisoara, Romania.
Medicina (Kaunas) ; 57(7)2021 Jun 28.
Article in English | MEDLINE | ID: covidwho-1288947
ABSTRACT
Coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic causing a serious global public health problem. The risk of vertical transmission of SARS-CoV-2 is still debated, and the consequences of this virus on pregnant women and their fetuses remain unknown. We report a case of pregnancy complicated with hydrops fetalis that developed 7 weeks after recovery from a mild SARS-CoV-2 infection, leading to intrauterine death of the foetus. Evidence of SARS-CoV-2 placentitis was demonstrated by the presence of viral particles in the placenta identified by immunohistochemistry. As we excluded all possible etiological factors for non-immunologic hydrops fetalis, we believe that the fetal consequences of our case are related to vertical transmission of SARS-CoV-2 virus. To the best of our knowledge, this is the second reported case in the literature of COVID-19 infection complicated with hydrops fetalis and intrauterine fetal demise.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / COVID-19 Type of study: Case report / Diagnostic study / Etiology study / Prognostic study Limits: Female / Humans / Pregnancy Language: English Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Medicina57070667

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / COVID-19 Type of study: Case report / Diagnostic study / Etiology study / Prognostic study Limits: Female / Humans / Pregnancy Language: English Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Medicina57070667