Early enteral nutrition improves the outcome of critically ill patients with COVID-19: A retrospective study.
Asia Pac J Clin Nutr
; 30(2): 192-198, 2021 Jun.
Article
in English
| MEDLINE | ID: covidwho-1289218
ABSTRACT
BACKGROUND AND OBJECTIVES:
To evaluate the nutritional status of critically ill patients with COVID-19 and to determine which route of nutrition support is advantageous. METHODS AND STUDYDESIGN:
This retrospective study was conducted in the ICU of a designated COVID-19 hospital. Patients were divided into an enteral nutrition (EN) group and parenteral nutrition (PN) group according to the initial route of nutrition support. NRS-2002 and NUTRIC were used to assess nutritional status. Blood nutritional markers such as albumin, total protein and hemoglobin were compared at baseline and seven days later. The primary endpoint was 28-day mortality.RESULTS:
A total of 27 patients were enrolled in the study - 14 in the EN group and 13 in the PN group - and there were no significant demographic differences between groups. Most patients (96.3% NRS2002 score ≥5, 85.2% NUTRIC score ≥5) were at high nutritional risk. There was no significant difference in baseline albumin, total protein and hemoglobin levels between groups. After 7 days, albumin levels were significantly higher in the EN group than in the PN group (p=0.030). There was no significant difference in the other two indicators. The 28-day mortality was 50% in the EN group and 76.9% in the PN group. Kaplan-Meier survival analysis revealed significant differences between the groups (p=0.030). Cox proportional risk regression indicated that route of nutrition support was also an independent prognostic risk factor.CONCLUSIONS:
The incidence of nutritional risk in critically ill patients with COVID-19 is very high. Early EN may be beneficial to patient outcomes.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Nutritional Status
/
Critical Illness
/
Enteral Nutrition
/
Parenteral Nutrition
/
COVID-19
/
Intensive Care Units
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
English
Journal:
Asia Pac J Clin Nutr
Journal subject:
Nutritional Sciences
Year:
2021
Document Type:
Article
Affiliation country:
Apjcn.202106_30(2).0002
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