Experimental Models for SARS-CoV-2 Infection.
Mol Cells
; 44(6): 377-383, 2021 Jun 30.
Article
in English
| MEDLINE | ID: covidwho-1289259
ABSTRACT
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is a novel virus that causes coronavirus disease 2019 (COVID-19). To understand the identity, functional characteristics and therapeutic targets of the virus and the diseases, appropriate infection models that recapitulate the in vivo pathophysiology of the viral infection are necessary. This article reviews the various infection models, including Vero cells, human cell lines, organoids, and animal models, and discusses their advantages and disadvantages. This knowledge will be helpful for establishing an efficient system for defense against emerging infectious diseases.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Organoids
/
SARS-CoV-2
/
COVID-19
/
Models, Theoretical
Limits:
Animals
/
Humans
Language:
English
Journal:
Mol Cells
Journal subject:
Molecular Biology
Year:
2021
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS