Author's overview: identifying SARS-CoV-2 antiviral compounds.
Biochem J
; 478(13): 2533-2535, 2021 07 16.
Article
in English
| MEDLINE | ID: covidwho-1290318
ABSTRACT
In response to the COVID-19 pandemic, we began a project in March 2020 to identify small molecule inhibitors of SARS-CoV-2 enzymes from a library of chemical compounds containing many established pharmaceuticals. Our hope was that inhibitors we found might slow the replication of the SARS-CoV-2 virus in cells and ultimately be useful in the treatment of COVID-19. The seven accompanying manuscripts describe the results of these chemical screens. This overview summarises the main highlights from these screens and discusses the implications of our results and how our results might be exploited in future.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Viral Nonstructural Proteins
/
Drug Evaluation, Preclinical
/
Small Molecule Libraries
/
SARS-CoV-2
Type of study:
Prognostic study
Topics:
Traditional medicine
Limits:
Animals
/
Humans
Language:
English
Journal:
Biochem J
Year:
2021
Document Type:
Article
Affiliation country:
Bcj20210426
Similar
MEDLINE
...
LILACS
LIS