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A Cluster Transmission of Coronavirus Disease 2019 and the Prevention and Control Measures in the Early Stage of the Epidemic in Xi'an, China, 2020.
Zhang, Hui; Song, Shuxuan; Chen, Zhijun; Bai, Miao; He, Zhen; Fu, Ting; Liu, Kun; Shao, Zhongjun.
  • Zhang H; Department of Prevention of Infectious Diseases, Xi'an Center for Disease Control and Prevention, Xi'an, Shaanxi, China (mainland).
  • Song S; Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Xi'an, Shaanxi, China (mainland).
  • Chen Z; Department of Epidemiology, Xi'an Center for Disease Control and Prevention, Xi'an, Shaanxi, China (mainland).
  • Bai M; Department of Epidemiology, The Infectious Disease Hospital of Shaanxi Province, Xi'an, Shaanxi, China (mainland).
  • He Z; Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Xi'an, Shaanxi, China (mainland).
  • Fu T; Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Xi'an, Shaanxi, China (mainland).
  • Liu K; Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Xi'an, Shaanxi, China (mainland).
  • Shao Z; Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Air Force Medical University, Xi'an, Shaanxi, China (mainland).
Med Sci Monit ; 27: e929701, 2021 Jun 14.
Article in English | MEDLINE | ID: covidwho-1292186
Semantic information from SemMedBD (by NLM)
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ABSTRACT
BACKGROUND At the beginning of the COVID-19 pandemic, a cluster outbreak caused by an imported case from Hubei Province was reported in Xi'an City, Shaanxi Province, China. Ten patients from 2 families and 1 hospital were involved in the transmission. MATERIAL AND METHODS We conducted an epidemiological investigation to identify the cluster transmission of COVID-19. The demographic, epidemiological, clinical, laboratory, and cluster characteristics were described and analyzed. RESULTS From January 27 to February 13, 2020, a total of 10 individuals were confirmed to be infected with SARS-CoV-2 by the nucleic acid testing of nasopharyngeal swabs from 2 families and 1 hospital. Among the confirmed cases, 7 had atypical clinical symptoms and 3 were asymptomatic. The median times from onset to diagnosis and to discharge were 3.5 days (range, 1-5 days) and 19.5 days (range, 16-38 days), respectively. There were 4 patients whose exposure dates were 1, 3, 3, and 2 days earlier than the onset dates of their previous-generation cases, respectively. Four prevention and control measures were effectively used to interrupt the disease transmission. CONCLUSIONS SARS-CoV-2 can be easily transmitted within families and in hospitals, and asymptomatic patients could act as a source of disease transmission. The results of this outbreak at the early epidemic stage support the recommendation that individuals with confirmed COVID-19 and all their close contacts should be subjected to medical quarantined observation and nucleic acid screening as early as possible, even if they do not have any symptoms. Meanwhile, people in high-risk areas should improve their protective measures.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Carrier State / Asymptomatic Infections / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Med Sci Monit Journal subject: Medicine Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Carrier State / Asymptomatic Infections / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Med Sci Monit Journal subject: Medicine Year: 2021 Document Type: Article