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COVID-19 vaccines are effective in people with obesity: A position statement from The Obesity Society.
Butsch, W Scott; Hajduk, Alexandra; Cardel, Michelle I; Donahoo, William T; Kyle, Theodore K; Stanford, Fatima Cody; Zeltser, Lori M; Kotz, Catherine M; Jastreboff, Ania M.
  • Butsch WS; Bariatric and Metabolic Institute, Department of Surgery, Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, Ohio, USA.
  • Hajduk A; Department of Internal Medicine (Geriatrics), Yale University School of Medicine, New Haven, Connecticut, USA.
  • Cardel MI; WW International, Inc., New York, New York, USA.
  • Donahoo WT; Department of Health Outcomes and Biomedical Informatics, University of Florida College of Medicine, Gainesville, Florida, USA.
  • Kyle TK; Department of Health Outcomes and Biomedical Informatics, University of Florida College of Medicine, Gainesville, Florida, USA.
  • Stanford FC; Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
  • Zeltser LM; ConscienHealth, Pittsburgh, Pennsylvania, USA.
  • Kotz CM; Department of Medicine (Neuroendocrine Unit), Department of Pediatrics (Division of Endocrinology), Nutrition Obesity Research Center at Harvard (NORCH), Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Jastreboff AM; Naomi Berrie Diabetes Center, Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.
Obesity (Silver Spring) ; 29(10): 1575-1579, 2021 10.
Article in English | MEDLINE | ID: covidwho-1293299
ABSTRACT
The position statement is issued by The Obesity Society in response to published literature, as well as inquiries made to the Society by patients, providers, Society members, policy makers, and others regarding the efficacy of vaccines in persons with obesity against SARS-CoV-2, the virus that causes COVID-19. The Obesity Society has critically evaluated data from published peer-reviewed literature and briefing documents from Emergency Use Authorization applications submitted by Pfizer-BioNTech, Moderna, and Johnson & Johnson. We conclude that these vaccines are highly efficacious, and their efficacy is not significantly different in people with and without obesity, based on scientific evidence available at the time of publication. The Obesity Society believes there is no definitive way to determine which of these three COVID-19 vaccines is "best" for any weight subpopulation (because of differences in the trial design and outcome measures in the phase 3 trials, elapsed time between doses, and regional differences in the presence of SARS-CoV-2 variants [e.g., South Africa B.1.351 in Johnson & Johnson trial]). All three trials have demonstrated high efficacy against COVID-19-associated hospitalization and death. Therefore, The Obesity Society encourages adults with obesity ≥18 years (≥16 years for Pfizer-BioNTech) to undergo vaccination with any one of the currently available vaccines authorized for emergency use by the US Food and Drug Administration as soon as they are able.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Societies, Medical / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Obesity Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Topics: Vaccines / Variants Limits: Adolescent / Adult / Aged / Humans / Middle aged / Young adult Language: English Journal: Obesity (Silver Spring) Journal subject: Nutritional Sciences / Physiology / Metabolism Year: 2021 Document Type: Article Affiliation country: Oby.23251

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Societies, Medical / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Obesity Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Topics: Vaccines / Variants Limits: Adolescent / Adult / Aged / Humans / Middle aged / Young adult Language: English Journal: Obesity (Silver Spring) Journal subject: Nutritional Sciences / Physiology / Metabolism Year: 2021 Document Type: Article Affiliation country: Oby.23251