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Visual comprehension and orientation into the COVID-19 CIDO ontology.
Zheng, Ling; Perl, Yehoshua; He, Yongqun; Ochs, Christopher; Geller, James; Liu, Hao; Keloth, Vipina K.
  • Zheng L; Computer Science and Software Engineering Department, Monmouth University, West Long Branch, NJ, USA. Electronic address: lzheng@monmouth.edu.
  • Perl Y; Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA.
  • He Y; Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Ochs C; Nokia Bell Labs, Murray Hills, NJ, USA.
  • Geller J; Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA.
  • Liu H; Columbia University Irving Medical Center, New York, NY, USA.
  • Keloth VK; Department of Computer Science, New Jersey Institute of Technology, Newark, NJ, USA.
J Biomed Inform ; 120: 103861, 2021 08.
Article in English | MEDLINE | ID: covidwho-1293913
ABSTRACT
The current intensive research on potential remedies and vaccinations for COVID-19 would greatly benefit from an ontology of standardized COVID terms. The Coronavirus Infectious Disease Ontology (CIDO) is the largest among several COVID ontologies, and it keeps growing, but it is still a medium sized ontology. Sophisticated CIDO users, who need more than searching for a specific concept, require orientation and comprehension of CIDO. In previous research, we designed a summarization network called "partial-area taxonomy" to support comprehension of ontologies. The partial-area taxonomy for CIDO is of smaller magnitude than CIDO, but is still too large for comprehension. We present here the "weighted aggregate taxonomy" of CIDO, designed to provide compact views at various granularities of our partial-area taxonomy (and the CIDO ontology). Such a compact view provides a "big picture" of the content of an ontology. In previous work, in the visualization patterns used for partial-area taxonomies, the nodes were arranged in levels according to the numbers of relationships of their concepts. Applying this visualization pattern to CIDO's weighted aggregate taxonomy resulted in an overly long and narrow layout that does not support orientation and comprehension since the names of nodes are barely readable. Thus, we introduce in this paper an innovative visualization of the weighted aggregate taxonomy for better orientation and comprehension of CIDO (and other ontologies). A measure for the efficiency of a layout is introduced and is used to demonstrate the advantage of the new layout over the previous one. With this new visualization, the user can "see the forest for the trees" of the ontology. Benefits of this visualization in highlighting insights into CIDO's content are provided. Generality of the new layout is demonstrated.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Diseases / Biological Ontologies / COVID-19 Topics: Vaccines Limits: Humans Language: English Journal: J Biomed Inform Journal subject: Medical Informatics Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Diseases / Biological Ontologies / COVID-19 Topics: Vaccines Limits: Humans Language: English Journal: J Biomed Inform Journal subject: Medical Informatics Year: 2021 Document Type: Article