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Personnel protection strategy for healthcare workers in Wuhan during the COVID-19 epidemic.
Hou, Fan Fan; Zhou, Fuling; Xu, Xin; Wang, Daowen; Xu, Gang; Jiang, Tao; Nie, Sheng; Wu, Xiaoyan; Ren, Chanjun; Wang, Guangyu; Lau, Johnson Yiu-Nam; Wang, Xinghuan; Zhang, Kang.
  • Hou FF; Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research, Guangzhou 510515, China.
  • Zhou F; Zhongnan Hospital of Wuhan University, Wuhan 430000, China.
  • Xu X; Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research, Guangzhou 510515, China.
  • Wang D; Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Xu G; Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Jiang T; Jingzhou Central Hospital, Jingzhou 434020, China.
  • Nie S; Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research, Guangzhou 510515, China.
  • Wu X; Zhongnan Hospital of Wuhan University, Wuhan 430000, China.
  • Ren C; Wuhan Kingmed Medical Laboratory, Wuhan, China.
  • Wang G; Department of Computer Science and Technology, Tsinghua University, Beijing 100084, China.
  • Lau JY; Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
  • Wang X; Zhongnan Hospital of Wuhan University, Wuhan 430000, China.
  • Zhang K; Center for Biomedicine and Innovations, Faculty of Medicine, Macau University of Science and Technology, Macau, China.
Precis Clin Med ; 3(3): 169-174, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-1294763
ABSTRACT

Objective:

To identify the effectiveness of a personnel protection strategy in protection of healthcare workers from SARS-CoV-2 infection.

Design:

During the COVID-19 pandemic, 943 healthcare staff sent from Guangzhou to Wuhan to care for patients with suspected/confirmed COVID-19 received infection precaution training before their mission and were equipped with Level 2/3 personal protective equipment (PPE), in accordance with guidelines from the National Health Commission of China. We conducted a serological survey on the cumulative attack rate of SARS-CoV-2 among the healthcare workers sent to Wuhan and compared the seropositive rate to that in local healthcare workers from Wuhan and Jingzhou.

Results:

Serial tests for SARS-CoV-2 RNA and tests for SARS-CoV-2 immunoglobulin M and G after the 6-8 week mission revealed a zero cumulative attack rate. Among the local healthcare workers in Wuhan and Jingzhou of Hubei Province, 2.5% (113 out of 4495) and 0.32% (10 out of 3091) had RT-PCR confirmed COVID-19, respectively. The seropositivity for SARS-CoV-2 antibodies (IgG, IgM, or both IgG/IgM positive) was 3.4% (53 out of 1571) in local healthcare workers from Wuhan with Level 2/3 PPE working in isolation areas and 5.4% (126 out of 2336) in healthcare staff with Level 1 PPE working in non-isolation medical areas, respectively. Conclusions and relevance Our study confirmed that adequate training/PPE can protect medical personnel against SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study Language: English Journal: Precis Clin Med Year: 2020 Document Type: Article Affiliation country: Pcmedi

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study Language: English Journal: Precis Clin Med Year: 2020 Document Type: Article Affiliation country: Pcmedi