Applications and analytical tools of cell communication based on ligand-receptor interactions at single cell level.
Cell Biosci
; 11(1): 121, 2021 Jul 03.
Article
in English
| MEDLINE | ID: covidwho-1296620
ABSTRACT
BACKGROUND:
Cellular communication is an essential feature of multicellular organisms. Binding of ligands to their homologous receptors, which activate specific cell signaling pathways, is a basic type of cellular communication and intimately linked to many degeneration processes leading to diseases. MAIN BODY This study reviewed the history of ligand-receptor and presents the databases which store ligand-receptor pairs. The recently applications and research tools of ligand-receptor interactions for cell communication at single cell level by using single cell RNA sequencing have been sorted out.CONCLUSION:
The summary of the advantages and disadvantages of analysis tools will greatly help researchers analyze cell communication at the single cell level. Learning cell communication based on ligand-receptor interactions by single cell RNA sequencing gives way to developing new target drugs and personalizing treatment.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Prognostic study
Language:
English
Journal:
Cell Biosci
Year:
2021
Document Type:
Article
Affiliation country:
S13578-021-00635-Z
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