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Homeostatic control of redox status and health.
Sies, Helmut; Ursini, Fulvio.
  • Sies H; Institute for Biochemistry and Molecular Biology I, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Ursini F; Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.
IUBMB Life ; 74(1): 24-28, 2022 01.
Article in English | MEDLINE | ID: covidwho-1296787
ABSTRACT
Research on oxidants and electrophiles has shifted from focusing on damage to biomolecules to the more fine-grained physiological arena. Redox transitions as excursions from a steady-state redox set point are continually ongoing in maintenance of redox balance. Current excitement on these topics results from the fact that recent research provided mechanistic insight, which gives rise to more concrete and differentiated questions. This Commentary focuses on redox eustress and the feedback restoration of steady state as concepts in active maintenance of physiological health, with brief discussion of redox stress response to viral infection, exemplified by COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Oxidation-Reduction / SARS-CoV-2 / COVID-19 / Homeostasis Limits: Humans Language: English Journal: IUBMB Life Journal subject: Molecular Biology / Biochemistry Year: 2022 Document Type: Article Affiliation country: Iub.2519

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Oxidation-Reduction / SARS-CoV-2 / COVID-19 / Homeostasis Limits: Humans Language: English Journal: IUBMB Life Journal subject: Molecular Biology / Biochemistry Year: 2022 Document Type: Article Affiliation country: Iub.2519